Ohio teen sentenced to life in Craigslist murders
















AKRON, Ohio (Reuters) – Seventeen-year-old Brogan Rafferty was sentenced to life in prison without parole on Friday for his role in the killing of three men and the attempted murder of another, some of whom were lured by a Craigslist ad promising work on an Ohio farm.


Rafferty was 16 when he was arrested in November 2011, but was tried as an adult. He was convicted late last month in the murders of David Pauley, 51, of Norfolk, Virginia; Ralph Geiger, 56, of Akron, Ohio; and Timothy Kern, 47, of Massillon, Ohio.













Prosecutors called the teen an apt pupil to the alleged trigger-man, Richard Beasley, 53, who is also charged in the murders.


Rafferty testified that he was terrified of the man he had considered a father figure and spiritual advisor after he saw Beasley shoot Geiger in the head execution-style.


During the trial, jurors heard testimony that the teen helped dig the graves for three of the men and was found in possession of guns and knives stolen from them after Beasley shot them.


Beasley’s trial is scheduled in the same courtroom for January 7. He faces the death penalty if convicted. Both Rafferty and Beasley’s attorneys are under a gag order and are not permitted to talk to the media.


In other incidents involving Craigslist and other social media, people advertising goods for sale or responding to ads have been attacked and killed.


In 2009, a former medical student was accused of killing a masseuse he met through Craigslist. In February, two men in Tennessee were accused of killing a man and a woman for “unfriending” the daughter of one of the suspects on Facebook.


(Reporting by Kim Palmer; Editing by Mary Wisniewski and David Brunnstrom)


Internet News Headlines – Yahoo! News



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Officials: Threats from Broadwell led to FBI probe









The scandal that brought down CIA Director David Petraeus started with harassing emails sent by his biographer and paramour, Paula Broadwell, to another woman, and eventually led the FBI to discover the affair, U.S. officials told The Associated Press on Saturday.

Petraeus quit Friday after acknowledging an extramarital relationship.









The official said the FBI investigation began several months ago with a complaint against Broadwell, a 40-year-old graduate of the U.S. Military Academy and an Army Reserve officer. That probe led agents to her email account, which uncovered the relationship with the 60-year-old retired four-star general, who earned acclaim for his leadership of the wars in Iraq and Afghanistan.

The identity of the other woman and her connection with Broadwell were not immediately known.

Concerned that the emails he exchanged with Broadwell raised the possibility of a security breach, the FBI brought the matter up with Petraeus directly, according to the official, who spoke on condition of anonymity because he was not authorized to publicly discuss the investigation. The FBI approached the CIA director because his emails in the matter were in most instances sent from a personal account, not his CIA one.

Petraeus decided to quit, abruptly ending a high-profile career that might have culminated with a run for the presidency, a notion he was believed to be considering.

Petraeus handed his resignation letter to President Barack Obama on Thursday, stunning many in the White House, the CIA and Congress. The news broke in the media before the House and Senate intelligence committees were briefed, officials say.

By Friday evening, multiple officials identified Broadwell, who spent the better part of a year reporting on Petraeus' time in Afghanistan.

Members of Congress said they want answers to questions about the affair that led to Petraeus's resignation.

House intelligence committee chairman Mike Rogers, R-Mich., and ranking member Dutch Ruppersberger, D-Md., will meet Wednesday with FBI deputy director Sean Joyce, and CIA acting director Michael Morell to ask questions, including how the investigation came about, according to a senior congressional staffer who spoke anonymously because he was not authorized to discuss the investigation publicly.

Petraeus has been married for 38 years to Holly Petraeus, the daughter of the West Point superintendent when he was a student at the New York school.

"He is truly remorseful about everything that's happened," said Steve Boylan, a retired army officer and former Petraeus spokesman who spoke with the former general on Saturday. In a phone call with Boylan Saturday, Petraeus lamented the damage he'd done to his "wonderful family" and the hurt he'd caused his wife.

"He screwed up, he knows he screwed up, now he's got to try to get past this with his family and heal," said Boylan.

Paula Broadwell interviewed the general and his close associates intensively for more than a year to produce the best-selling biography, "All In: The Education of General David Petraeus," which was written with Vernon Loeb, a Washington Post editor, and published in January. Since Petraeus's resignation on Friday, the book jumped from a ranking on Amazon of 76,792 on Friday to 111 by mid-Saturday.

The CIA was not commenting on the identity of the woman with whom Petraeus was involved.

Broadwell, who is married with two young sons, has not responded to multiple emails and phone messages. Broadwell planned to celebrate her 40th birthday party in Washington this weekend, with many reporters invited. But her husband emailed guests to cancel the event late Friday.

CIA officers long had expressed concern about Broadwell's unprecedented access to the director. She frequently visited the spy agency's headquarters in Langley, Va., to meet Petraeus in his office, accompanied him on his punishing morning runs around the CIA grounds and often attended public functions as his guest, according to two former intelligence officials.

As a military intelligence officer in the Army Reserve, Broadwell had a high security clearance, which she mentioned at public events as one of the reasons she was well-suited to write Petraeus's story.

But her access was unsettling to members of the secretive and compartmentalized intelligence agency, where husbands and wives often work in different divisions, but share nothing with each other when they come home because they don't "need to know."

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Sony Animation preps sequel to hit “Hotel Transylvania”
















NEW YORK (TheWrap.com) – Sony Pictures Animation will make a sequel to “Hotel Transylania,” one of the year’s surprise hits, a spokesman for the studio told TheWrap.


Tentatively titled “Hotel Transylvania 2,” the film is set for a 2015 release. There is no director attached at the moment. Genndy Tartakovsky, who directed the first one, will be helming Sony Pictures Animation‘s “Popeye.”













Hotel Transylvania” opened to $ 42.5 million at the domestic box office and $ 50.6 worldwide, setting a new record for a September opening. It has grossed more than $ 250 million at the global box office so far.


Adam Sandler voiced the character of Dracula, who owns the titular five-star resort designed as a place for monsters to relax away from humans. Other monsters such as Murray the Mummy (Cee Lo Green), Frankenstein’s Monster (Kevin James) and Griffin the Invisible Man (David Spade) descend upon the hotel for the 118th birthday of Dracula‘s daughter Mavis (Selena Gomez).


Movies News Headlines – Yahoo! News



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U.S. Extends Deadline on Health Coverage for States





WASHINGTON — With many states lagging far behind schedule, the Obama administration said Friday that it would extend the deadline for them to submit plans for health insurance exchanges, the online markets where millions of Americans are expected to obtain private coverage subsidized by the federal government.




The original Nov. 16 deadline will be extended to Dec. 14 — and in some cases to Feb. 15, the administration said.


The Congressional Budget Office predicts that 25 million people will obtain coverage through the new online shopping malls known as insurance exchanges. Most of them will receive federal subsidies averaging more than $5,000 a year per person to help them pay premiums.


Every state is supposed to have an exchange by Jan. 1, 2014, when the federal government will require most Americans to have insurance. Many states delayed work on the exchanges to see the outcome of a Supreme Court case challenging the health care law, then waited to see if President Obama would be re-elected.


If a state wants to run its own exchange, its governor still must submit a declaration of intent — generally a brief letter of one or two pages — by Nov. 16. But states will have more time to submit the detailed applications required by federal officials.


The White House has repeatedly said that states were making excellent progress toward creation of the exchanges, even as Republican governors and state legislators expressed ambivalence or outright opposition. In addition, state officials who want to establish exchanges said they were having difficulty because Mr. Obama had yet to issue crucial regulations and guidance.


In a letter to governors on Friday, Kathleen Sebelius, the secretary of health and human services, said that many states had asked for “additional time” to submit applications indicating whether they wanted to run their own exchanges or help the federal government run exchanges in their states.


Under the Affordable Care Act, the federal government will run the exchanges in any states that are unable or unwilling to do so. Fewer than half the states have indicated that they will set up their own exchanges.


If states want to run their own exchanges, Ms. Sebelius said, they will have until Dec. 14 to submit applications, or blueprints. And if states want to run exchanges in partnership with the federal government, she said, they will have until Feb. 15 to file applications.


Ms. Sebelius said the new timetable would not defer the dream of affordable insurance for millions of Americans.


“Consumers in all 50 states and the District of Columbia will have access to insurance through these new marketplaces on Jan. 1, 2014, as scheduled, with no delays,” Ms. Sebelius told governors. “This administration is committed to providing significant flexibility for building a marketplace that best meets your state’s needs.”


Senator Orrin G. Hatch of Utah, the senior Republican on the Senate Finance Committee, said the change in the deadline was “no surprise” because the White House had not given states enough information or guidance to make decisions.


“Frankly,” Mr. Hatch said, “the fact that the exchanges are such a mess is pretty emblematic of how flawed the president’s health law is — with states having to bear the brunt.”


Representative Charles Boustany Jr. of Louisiana, a spokesman for House Republicans on health policy, said he doubted that extending the deadline would make the law any more workable.


Even in states where governors want to establish insurance exchanges, they need legal authority to do so, and Republican legislators have balked in some states.


Federal officials hope that fierce competition among insurers offering health plans in the exchanges will drive down premiums.


Joel S. Ario, a former director of the federal office for insurance exchanges who now advises states as a consultant at Manatt Health Solutions, said: “The administration’s decision is a good move. It increases the chances that more states will opt for a partnership exchange, rather than default to a federal exchange.”


An administration official said that Mr. Obama was on schedule in carrying out the law, and that starting in October, Americans will be able to enroll in health plans for coverage starting in January 2014.


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Walmart Black Friday 2012 coming even earlier









Cierra Hobson is a die-hard Black Friday shopper.

Every year she queues in front of one of her favorite stores, where she waits, in her pajamas, in hopes of bagging a good deal.

This year, Hobson and other deal-seekers will find some twists on the post-Thanksgiving Day ritual: coupons delivered via mobile phones and deeper discounts, maneuvers designed to make shopping easier for consumers and to set retailers on a strong start to the biggest shopping period of the year. But perhaps the biggest change will be an earlier start to the holiday rush.

Black Friday historically launched the day after Thanksgiving. But in recent years, stores have opened at 4 a.m., then midnight. Last year, retailers created a stir by opening at 10 p.m. Thursday. This year, Sears and Wal-Mart announced plans to open at 8 p.m.

"The name of the game this holiday season is who can do it best," said National Retail Federation spokeswoman Kathy Grannis.

"When (early openings) started in 2009, things were a little bit worse off in terms of consumer confidence," Grannis added. "At that point it was very necessary for retailers to get out there before anybody else, and that literally meant before midnight."

This year, holiday spending is expected to rise 4.1 percent, according to the retail federation. Last year, more than 24 percent of Black Friday shoppers were out before midnight and nearly 39 percent of shoppers were in the stores before 5 a.m.

Wal-Mart plans to greet shoppers with the likes of $89 Wii consoles and a $38 Blu-ray player. At Sears, there will be perks on sale items for members of its shopper loyalty program.

Both retailers are touting in-store pickup, allowing customers to buy items online and pick them up at the store, avoiding checkout lines.

The Disney Store plans to begin offering Black Friday deals on the Monday before Thanksgiving, though Disney stores will open at midnight in some markets and 5 a.m. in others. Ads leaked to Internet deal sites say Target stores will open at 9 p.m. on Thanksgiving.

Last year, Wal-Mart recorded its most customer traffic at 10 p.m. on Thanksgiving night, said spokesman Steven Restivo, adding that the retailer relied on focus groups, online surveys and other feedback to help it decide to open two hours earlier this year. "Our customers told us they loved our Thanksgiving event last year and wanted it again."

At Sears, staying open 26 consecutive hours through Black Friday gives its customers the flexibility they want and makes good business sense, said spokesman Brian Hanover.

"There's a segment of Sears customers who want that thrill of holiday shopping to start as soon as their Thanksgiving dinner ends," he said. "Traditionalists," he added, can wait for door busters at 4 a.m.

Despite discounts that often go beyond 50 percent, stores still make money on the sales, retail experts say. That's because shoppers in physical stores tend to spend more than they planned, said Sanjay Dhar, professor of marketing at the University of Chicago Booth School of Business.

In the store, "you end up making purchases that aren't as marked down, in addition to the door-buster deals," he said.

Opening earlier and staggering door-buster deals is not only a good way to make money, but it's also necessary for crowd control, retail watchers say. In 2008, a store employee was trampled to death in a Black Friday door-buster stampede at a Long Island, N.Y., Wal-Mart.

Hobson said she doesn't plan to start shopping Thanksgiving night, but she said she'll be up before dawn to catch sales at Express, a clothing store.

"Just knowing that everybody is doing the same thing I'm doing on the same day feels like the beginning of Christmas," she said.

Others worry that super-early openings could backfire.

Sheri Petras, CEO of CFI Group, a Michigan-based consultancy, said store employees grumpy from having to leave their Thanksgiving festivities will take out their anger on customers.

"Consumers will not spend as much with cranky employees," she said.

Some employees at Wal-Mart, Sears and Target say they'd like the day off.

Change.org, an activist website, said Friday that more than 20 new petitions were submitted by employees and consumers asking retailers to reconsider their Thanksgiving evening openings.

It's the second year the website has administered petitions calling for retailers to stick to traditional Black Friday openings.

In a statement distributed by OUR Walmart, a labor rights group, Wal-Mart employee Mary Pat Tifft, of Wisconsin, said she would be "devastated" if she had to work on Thanksgiving, because she is expecting her son home from Afghanistan for the holiday.

"This early opening is one more example of Walmart's disconnect with the workers who keep its stores running and disregard for all of our families. As the largest employer in the country, Walmart could be setting a standard for businesses to value families, but instead, this is one more Walmart policy that hurts the families of workers at its stores," she said.

crshropshire@tribune.com

Twitter @corilyns



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Philip Roth Is Retiring; Amazon Glitch Disables Buy Buttons
















Today in books and publishing: Philip Roth confirms his retirement; Amazon‘s mysteriously vanishing buy buttons; Kobo expands to Italy, Kindle considers China; cities in literature.


RELATED: Trikes, a Mustache, and Andy Warhol













Philip Roth wraps it up. One of America’s most celebrated living novelists has been hinting at retirement for a while now. But he didn’t choose to make a big announcement in a prominent stateside literary organ like The New York Review of Books. He chose instead to let it out in interviews with the foreign press over recent weeks. Last month he told Nelly Kaprièlian of French magazine Les Inrockuptibles that he hasn’t written new material in three years, and doesn’t plan to write any new novels. “To tell you the truth, I’m done,” he said frankly, “Nemesis will be my last book … Enough is enough! I no longer feel this fanaticism to write that I have experienced in my life.” He said the same thing in an interview with Italian magazine La Repubblica earlier this month. His publisher Houghton Mifflin confirmed that Roth is entering retirement. It looks the 74-year-old writer will have plenty of time to go over his life story and thoughts on literature with his new biographer, Blake Bailey. [Salon]


RELATED: How to Game Amazon Prime; Random House Consolidates in the Spanish Market


Where did Amazon‘s buy buttons go? Late last night, customers looking to replenish their Kindles with fresh e-books were probably quite frustrated. No matter how hard anyone clicked, there was no way to purchase e-books from Penguin, Random House, Macmillan, Simon & Schuster, Hachette, and HarperCollins through Amazon. A company spokesperson later confirmed that it was just a technical slip-up, and buy buttons were quickly restored. But given Amazon’s propensity to punish publishers that don’t bend to its will with disabled buy buttons, this brief black-out set off a minor panic in publishing land. Why were only Big Six publishers affected? Did it have anything to do with the ongoing agency pricing legal battles or the Penguin Random House merger? Though it seems to have been nothing more serious than a technical goof, it’s a stark reminder that Amazon has the ability—as well as the leverage—to shut down publishers’ most important connection with consumers at the click of a mouse. [New York Observer]


RELATED: Chart: The Rapid Gains of the E-book


E-reading takes a global turn. E-books may be taking firm holds in the U.S., but they have a long way to go before they became the global format of choice for readers. Italy may be going in an increasingly digital direction soon, with the country’s largest bookseller Mondadori Group partnering with Kobo to stock Touch e-readers in its hundreds of stores. 34,000 e-books will be available for Italian readers. China is another largely untapped market, one that Amazon is eyeing enviously. ZDNet’s Liau Yun Qing reports that Kindles may become available there as early as this month. “If Amazon brings its e-reader to China, it will face competition from Chinese e-commerce player Dangdang which launched its e-reader in July at a retail price of 599 yuan (US$ 79),” she writes. “In comparison, the cheapest Kindle Paperwhite e-reader, which includes “Special Offers”, retails at US$ 119 in the United States.” [ZDNet]


RELATED: New Batman Comic Postponed; Books Banned in China Thrive in Hong Kong


Cities in literature. Mark Binelli’s new book Detroit City Is the Place to Be is all about the Motor City—its ascent during America’s industrial golden age, and its struggle to redefine itself. Given his obsession with the urban, Publishers Weekly decided to tap Binelli for a list of his favorite books that take specific cities as a central theme. It’s more interesting than most lists on this subject might have been. For instance, he shines a light on Joan Didion not for her classic takes on San Francisco or New York, but for her book Miami. And his favorite books to take on New York—Ben Katchor’s The Jew of New York and Joseph Mitchell’s Up in the Old Hotel—are refreshing inclusions. His favorite book about Detroit, Elmore Leonard’s City Primeval, is also a bit surprising. [Publishers Weekly]


Gadgets News Headlines – Yahoo! News



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Illinois Tollway 2013 budget to be subject of hearings









The Illinois Tollway’s proposed 2013 budget will be the subject of two public meetings next week and is available on-line for review and comment, the agency has announced.

The tentative spending plan covers annual maintenance and operations on the tollway system, as well as $922 million in capital projects scheduled to be underway next year.

Tollway officials said they are encouraging the public to comment on the budget.

“This budget doubles the tollway’s capital spending over 2012, prioritizes improvements to our roadways and customer service, identifies new efficiencies and keeps our growth in baseline operating costs to just 4 percent,” Executive Director Kristi Lafleur said in a statement.

The tollway will hold a hearing Tuesday, Nov. 13, at 6 p.m. at its headquarters at 2700 Ogden Ave. in Downers Grove.

The hearing will be broadcast live on the tollway’s website, illinoistollway.com.

Public comments will be accepted at the hearing as well as via the webcast.

The tollway will hold an open house on Wednesday, Nov. 14, from 3 to 6 p.m. at the O’Hare Oasis on the Tri-State Tollway (Interstate 294) in Schiller Park.

The public will be able to view displays and a budget overview and ask questions of tollway representatives, the agency said. Public comments will be accepted in writing or can be made to a court reporter.

The tollway has also posted a webinar about the proposed budget on the website.
A copy of the tentative budget is posted on the tollway’s website or may be requested by contacting the agency at 630-241-6800.

Comments may also be mailed to 2700 Ogden Ave., Downers Grove, IL 60515.





After the tollway’s board has reviewed the public comments and any changes have been incorporated, a final budget will be presented for approval by the board at its Dec. 13 meeting.

“The board is committed to hearing the public’s opinions on how their tolls are spent,” Tollway Chairwoman Paula Wolff said in a statement. “As we begin our review, we look forward to considering their ideas about this budget plan.”

The tollway will spend $771 million next year as it starts rebuilding and widening the Jane Addams Memorial Tollway and the Elgin-O'Hare bypass project, according to the proposed budget.

Also planned are completion of the new interchange on the Addams (I-90) at Illinois Highway 47 near Huntley and work on the new connection between the Tri-State Tollway (I-294) and I-57 near Markham.

All told, the tollway plans to spend $922 million for construction and expansion of the system, officials said. That's double the agency's spending this year.

To help pay for the projects, the tollway anticipates taking in $977 million from tolls in 2013 -- thanks to the 87.5 percent increase that went into effect Jan. 1. No new tolls are expected in 2013, Lafleur said.

The tollway plans to issue as much as $1 billion in bonds next year for its projects and future capital needs, officials said.

That's in addition to its $3.91 billion in outstanding debt as of Jan. 1, 2013.

All that spending is part of the tollway's $12.1 billion public works program to expand and improve the 296-mile system. The program, known as Move Illinois, is entering the second of 15 years.

As far as agency operations are concerned, officials say costs will increase 4 percent.
The addition of 16 new positions in engineering and finance for Move Illinois will be offset by reductions in toll operations, officials said.

The budget includes savings of more than $5 million, officials said.

rwronski@tribune.com
Twitter: @richwronski





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Frankfurt gears up for Gangnam Style at MTV awards
















FRANKFURT (Reuters) – The MTV Europe Music Awards will rock Frankfurt’s Festhalle concert venue on Sunday, with Barbadian R&B singer Rihanna leading the nominations and all eyes on Korean dance sensation Psy.


Psy‘s hit “Gangnam Style“, which is up for the Best Video award, has been viewed more than 670 million times and received a record-breaking 4.9 million “likes” on Facebook since being released in mid-July.













The satirical video featuring Psy‘s horse riding-inspired dance has sparked a wave of copycat versions from Eton schoolboys to Californian lifeguards and has even caught the attention of United Nations chief Ban Ki-moon.


Psy will become the first South Korean artist to perform at the annual awards, one of the pop industry’s biggest nights outside the United States, when he takes the stage on Sunday.


German model and presenter Heidi Klum, who this year filed for divorce from singer husband Seal, will host the awards and said she had been practicing her Gangnam moves in case she gets called on to dance.


“My kids are obsessed with the song, even though it’s Korean and they have no idea what he’s talking about,” she told reporters ahead of the event.


Klum, who comes from the town of Bergisch Gladbach just two hours away from the 2012 host city, is also looking forward to some home comforts.


“I’ll be eating a lot of German food,” she said, adding jokingly that she would probably eat too much schnitzel and “gain a few pounds.”


Despite being billed as the Europe Music Awards, the vast majority of nominees are traditionally North American, and 2012 is no exception.


Alongside Psy, acts due to take the stage at the show include country singer Taylor Swift, 14-time Grammy winner Alicia Keys, the Killers and Carly Rae Jepsen.


“OLD WAYS” STILL COUNT


In a world where careers are so often launched by social media websites like YouTube, some young artists said there was still a role for more established platforms such as MTV and mainstream television.


American indie-pop band fun., who are up for three awards, hit the big time after the song “We Are Young” was featured in an advert for Chevrolet during the U.S. Superbowl.


“I don’t think that you can ever replace the impact that music videos have,” the band’s guitarist Jack Antonoff told Reuters when asked about the importance of MTV against social media channels.


“I think the more that social media takes over, the more importance you put upon the old ways.”


MTV said this week that it had become the first company to reach one million followers on Instagram, the fast-growing photo-sharing application developer.


Heading the nominations is party-loving Rihanna, with nods in six categories, including Best Song and Best Video for “We Found Love”.


Following close behind with five nominations is country star Swift, and other top nominees include Justin Bieber and Katy Perry, with four each, while Lady Gaga, who cleaned up last year with four prizes, is in the running for three awards.


Rihanna is favorite for Best Song and Best Female, according to odds offered by British bookmakers William Hill, while Gangnam Style is tipped to win Best Video.


The EMA awards were last held in Frankfurt in 2001. Last year’s awards in Belfast attracted 23 million viewers on all platforms and 158 million votes worldwide.


Following are the main nominations in 2012:


BEST SONG: Carly Rae Jepsen/Call Me Maybe; Rihanna feat. Calvin Harris/We Found Love; Gotye/Somebody That I Used To Know; Pitbull feat. Chris Brown/International Love; fun. feat. Janelle Monáe/We Are Young


BEST NEW: Rita Ora; fun.; One Direction; Lana Del Rey; Carly Rae Jepsen


BEST FEMALE: Rihanna; Katy Perry; P!nk; Taylor Swift; Nicki Minaj


BEST MALE: Justin Bieber; Kanye West; Flo Rida; Pitbull; Jay-Z


BEST POP: Justin Bieber; No Doubt; Katy Perry; Taylor Swift; Rihanna


BEST LIVE: Taylor Swift; Lady Gaga; Jay-Z & Kanye West; Green Day; Muse


BEST HIP HOP: Jay-Z & Kanye West; Nas; Rick Ross; Drake; Nicki Minaj


BEST ROCK: Linkin Park; Green Day; Muse; The Killers; Coldplay


BEST ELECTRONIC: David Guetta; Swedish House Mafia; Avicii; Skrillex; Calvin Harris


BEST ALTERNATIVE: Jack White; The Black Keys; Arctic Monkeys; Florence + The Machine; Lana Del Rey


BEST VIDEO: M.I.A./Bad Girls; Lady Gaga/Marry The Night; Katy Perry/Wide Awake; Rihanna feat. Calvin Harris/We Found Love; PSY/Gangnam Style.


(Reporting by Victoria Bryan and Maria Sheahan; editing by Mike Collett-White)


Music News Headlines – Yahoo! News



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Malaria Vaccine Candidate Produces Disappointing Results in Clinical Trial


The latest clinical trial of the world’s leading malaria vaccine candidate produced disappointing results on Friday. The infants it was given to had only about a third fewer infections than a control group.


But researchers said they wanted to press on, assuming they keep getting financial support, because the number of children who die of malaria is so great that even an inefficient vaccine can save thousands of lives.


Three shots of the vaccine, known as RTS, S or Mosquirix and produced by GlaxoSmithKline, gave babies fewer than 12 weeks old 31 percent protection against detectable malaria and 37 percent protection against severe malaria, according to an announcement by the company at a vaccines conference in Cape Town.


Last year, in a trial in children up to 17 months old, the same vaccine gave 55 percent protection against detectable malaria and 47 percent against severe malaria.


The new trial “is less than we’d hoped for,” Moncef Slaoui, chairman of research and development at Glaxo, said in a telephone interview. “But if a million babies were vaccinated, we would prevent 260,000 cases of malaria a year. This is a disease that kills 655,000 babies a year — 31 percent of that is a very large number.”


The company, which has already spent more than $300 million on the vaccine, wants to keep forging ahead, Mr. Slaoui said, “but it is not just our decision.”


It also depends on the PATH Malaria Vaccine Initiative, which has put more than $200 million of its Bill and Melinda Gates Foundation financing into the vaccine, and on the World Health Organization, which has helped talk seven African countries into allowing the vaccine to be tested on their children.


The Gates Foundation declined to say how much money it was ultimately prepared to spend on an imperfect vaccine; this set of trials is set to go into 2014.


“The efficacy came back lower than we had hoped, but developing a vaccine against a parasite is a very hard thing to do,” Bill Gates said in a prepared statement. “The trial is continuing, and we look forward to getting more data to help determine whether and how to deploy this vaccine.”


All the families in the trial were given insecticide-treated mosquito nets and encouraged to use them; 86 percent did, so the vaccine’s results were achieved on top of other anti-malaria measures.


RTS, S contains a protein found on the parasite’s surface that provokes an immune reaction. It was first identified decades ago by two New York University scientists, Ruth and Victor Nussenzweig. The vaccine was developed by Glaxo in Belgium and initially tested on American volunteers by the Walter Reed Army Institute of Research.


When the Gates Foundation began focusing on global health in the early part of this century, it was one of the first projects the foundation adopted. Different ways to make the vaccine more effective, including adding different boosters and giving more shots, are being experimented with. Other vaccines using different ways to provoke an immune reaction exist, but none are as far along in clinical trials.


Like an H.I.V. vaccine, one against malaria has proved an elusive goal. The parasite morphs several times, exhibiting different surface proteins as it goes from mosquito saliva into blood and then into and out of the liver. Also, even the best natural “vaccine” — catching the disease itself — is not very effective. While one bout of measles immunizes a child for life, it usually takes several bouts of malaria to confer even partial immunity. Pregnancy can cause women to stop being immune, and immunity can fade out if someone moves away from a malarial area — presumably because they no longer get “boosters” from repeated mosquito bites.


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Sandy to raise U.S. used-car prices









The estimated 250,000 cars flooded by Superstorm Sandy on the East Coast will drive up used-car prices, even as far away as California.

The supply shortage comes on the heels of an already tightened used-car market in the wake of the recession, when new car sales dried up. Some experts say prices could rise $700 to $1,000 on the typical used car in the short term. Although those effects will be felt most acutely near the flood zone, the increasingly digital and national market for used cars will spread the price shocks widely.

The flood of Sandy-damaged cars further poses the risk that many will wind up in the hands of unscrupulous dealers peddling to unwitting consumers. The vehicles pose both financial and health risks.





Test your knowledge of business news

"Cars that have been submerged in saltwater, and contaminated by bacteria and various toxins, will soon start to appear all over the country, even in states far from the center of the storm," said Rosemary Shahan, president of Consumers for Auto Reliability and Safety.

Shahan said there were cases of Nissan vehicles flooded by Hurricane Katrina auctioned as "new" as far away as California after that storm.

She urged shoppers to look for signs of flood damage, including engines that hesitate or run roughly, musty interior smells or signs of silt residue or premature rust.

Buyers should also run the vehicle information number through the National Motor Vehicle Title Information System at vehiclehistory.gov. Insurers, salvage pools, auctions and junkyards in all 50 states are required to report all total-loss vehicles to this federal database within 30 days, Shahan said.

For new vehicles or those still within the factory warranty period, shoppers who suspect flood damage should call the manufacturer to ask if they will honor the warranty, which is typically nullified for flooded cars. If the vehicle was registered as a flood vehicle, the manufacturer won't honor the warranty, and the buyer will know there is a problem.

Although properly restored and titled salvage or flooded vehicles can be an "economical option," consumers should understand what they are getting.

"There is always a chance that there will be problems down the road with corrosion or malfunctions in the electrical systems," said Bob Passmore, senior director at the Property Casualty Insurers Assn. of America.

Rising prices caused by the storm might be one reason why consumers would turn to such cheaper options or fall victim to an attractively priced vehicle with hidden flood damage.

Prices are already comparatively high for late-model used cars, according to industry analysts. That's because of the low number of new cars sold in 2009 and 2010, which also slowed the flow of trade-ins into the used-car market. Leases, a major source of used cars, nearly disappeared.

Now the flood of Sandy-damaged cars is putting more pressure on the tight supply of late-model cars. Prices will go up at least 0.5% to 1.5% in December, said Jonathan Banks, an analyst with the National Automobile Dealers Assn. The dealer group said that amounts to a little more than $50 to $175 for the average used vehicle.

Auto information company Edmunds.com has a much higher estimate, saying that used-car prices will climb $700 to $1,000 "in the short term."

The price hikes will be highest on the East Coast but felt nationally, Banks said.

"We have seen a trend for dealers, regardless of where they are located, buying inventory online, and that means that geography is not as important as in the past," he said. "It used to be that dealers would buy cars from a physical auction near their dealership."

Pulling such a huge number of vehicles out of the U.S. fleet will have an effect at the national level, Banks said.

The problem is compounded by at least tens of thousands of new cars that were destroyed both at dealerships and storage yards in parts of New York and New Jersey hit hardest by the storm.

"Many dealers lost a significant amount of inventory. One Honda dealer told me he lost 600 new units," Banks said.

Fisker Automotive Inc., the Anaheim maker of $100,000 plug-in hybrid sports cars, said it lost 338 vehicles, with a retail value of nearly $34 million, at a port storage facility in New Jersey. Toyota Motor Corp. has said it might have lost as many as 4,500 new Toyota, Scion and Lexus vehicles to flooding and storm damage. American Honda Motor Co. said that more than 3,000 new vehicles at its dealers and storage yards suffered flood damage.

All this is going to create problems for consumers in the storm region who need to replace their rides quickly.

"Prices could really shoot up for consumers buying cars right away, because they will run into a severe inventory shortage," Banks said.

The dealers group believes that some replacement buying will start this month but will pick up in December and run through February. Banks expects that about 30% of buyers will purchase new cars and the remainder will choose used cars.

The buying, however, should provide a boost for the economy, said Edmunds.com Chief Economist Lacey Plache.

"Even if 100,000 damaged vehicles are replaced by the end of the year, it could boost auto sales 3% to 4% for the quarter," Plache said. "That has a positive effect on the economy overall."

jerry.hirsch@latimes.com





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